Last week, we discussed the four successful tests of the S&P 500 1320 level, and it turned out that the S&P required yet another test down to 1326 last Friday to clear the decks. It then shot up to the top of the 1340-to-1370 range that has defined most of the action since the middle of January. And after pausing a day to let the swing traders make the mistake of going short at 1370, it broke through that level on Tuesday.
This is a very good setup for further gains on the S&P, as each dip like today’s back to the 1370 area, or maybe future tests down to 1340 or even to 1326, will bring the bears out of their caves to say: “I told you so.” And that maintains the Wall of Worry (based on sub-prime mortgages, the credit lockup, a recession and weak consumer spending — all old news) that lets the market climb higher and higher after each dip. I am still focused on 1395, 1440, 1555, 1880 and maybe 2100 as the next 14 months play out to an April 2009 top.
A while ago, some friends at Visa told me: “Don’t worry about the banks… when Visa files to go public, you’ll see huge gains on their Visa equity positions.” Visa, of course, is owned by the banks, and on Monday Visa filed what will be the largest IPO in history — $19 billion. That will obliterate the current record of $10.6 billion set by AT&T Wireless in 2000. The current #2 deal is Kraft Foods’ $8.7 billion IPO in 2001. The Visa deal will probably be bigger than both of them combined.
Will it sell? Visa is a card processor, not a lender, so they have no consumer default problems. In addition to being the largest U.S. card processor, they have a worldwide business with 1.5 billion credit cards outstanding and are in many countries that are still in the early days of using credit cards. MasterCard stock is up 400% since its IPO two years ago. So yes, the Visa IPO will sell out. The company will list on the New York Stock Exchange under the symbol “V.”
More than half of the initial proceeds, or about $10 billion, will go to selling shareholders like Citigroup, Bank of America and JPMorgan Chase. These companies will then use the dough to rebuild their balance sheets to offset mortgage credit losses, and, on top of this, they’ll still own lots of Visa’s stock so they can benefit from its move to a public market value.
This week, Congress raised the dollar limits on the amount of mortgages Fannie Mae and Freddie Mac can hold. Fed Chairman Bernanke virtually promised more rate cuts, saying that he would deal with inflation later. The new, much higher limit on the size of a mortgage that government entities can buy went into effect. So anyone who is worrying about these old-news issues is fighting not only the Fed but the current Administration, both houses of Congress and most of the Presidential candidates, all of whom are determined to paper over the mess and put off the day of reckoning. I think that they will be able to do that one last time, creating a major financial bubble over the next 14 months. Be fully invested in our stocks to take advantage of it.
Biotech MegaShift
CombinatoRx (CRXX) held their analyst day in New York recently. Overall, they raised guidance for 2008 to revenues of $15 million to $20 million; a net loss of $49 million to $55 million, excluding stock option expenses and depreciation; and ending cash and equivalents of $58 million to $64 million.
We should see clinical data from at least four programs:
- Crx-102: Phase IIb clinical data for arthritis, and publications demonstrating corticosteroid dissociation through CRx-102′s unique mechanism of action;
- Crx-191: Phase II clinical data for plaque psoriasis;
- Crx-197: Phase II clinical data for atopic dermatitis;
- Crx-401: Phase II clinical data in Type-2 diabetes.
The company will also decide what programs to advance into Phase I clinical trials. I expect Crx-808 for hepatitis C to make the cut. There are other compounds for B-cell cancers, skin diseases and eye diseases in development.
My thesis in recommending this stock was that their proprietary technology of combining two already-approved drugs would spin off a lot of product candidates that can be partnered, while lowering the scientific risk. The biggest risk in this approach is showing efficacy at a safe dosing level in Phase II trials. The second biggest risk is striking partnership deals that bring in cash to continue discovery efforts and also backend royalties that will get Wall Street excited. I think that we get paid this year, so buy CRXX under $7 for a $16 target after they have results from the Phase II trials and start announcing partners for Phase III trials.
eResearch (ERES) reported a very good December quarter, with sales up 45% to a record $28.9 million compared with the $28.6 million consensus. They did 10 cents a share, well over the eight-cent consensus. ERES guided revenues up for the March quarter, and they are now looking for $31 million to $33 million in revenues, compared with the consensus for $29.6 million, and eight cents to 10 cents a share, bracketing the nine-cent estimate. For the 2008, they said that revenues will hit $130 million to $137 million, well over the $122.1 million consensus, with earnings in the 42-cent to 46-cent range, again well over the 41-cent consensus.
The strong order growth that we have seen for several quarters, with record bookings in 2007, is finally translating into strong revenue growth. We seem to be in a new world where the old six-month delay between an order and the beginning of a clinical trial has stretched out to 12 to 15 months. But the delay has stabilized there, so we are finally getting the revenue growth that I expected to start two or three quarters ago. With the backlog up 45% from last year, growth will continue.
On the conference call, management said that prices are stabilizing, as demonstrated by their over-28% pre-tax profit margins. Their pipeline of new opportunities that have not yet turned into bookings is growing as the pharma and biotech companies focus on meeting the FDA’s cardiac safety requirements. The CEO said: “The overall clinical trials business environment for Cardiac Safety and the need for technology-based solutions in clinical trials are as healthy as we have seen in a long time.”
The stock was up $1.80 yesterday and today in response to the conference call, but this is just the beginning. There are lots of investors looking for revenue momentum, earnings momentum and/or upside surprises, and we should see them piling into ERES over the next year. ERES is both a Top Buy and a very timely buy up to my $16 buy limit, and I expect to see my $30 target price before the broad market peaks in April 2009.
Geron (GERN) reported this morning, with a $16.5-million loss for the quarter, or 22 cents a share. They have $208 million in cash and no debt. The big news, though, was not earnings; it was that they developed a stem cell therapy that enabled paralyzed rats to walk. There have been no dangerous side effects in 2,000 animal trials. The therapy uses human embryonic stem cells, and it is not complicated in theory. Myelin is a fatty substance that provides insulation for nerve fibers, which is important for motor function. When a spine is damaged, myelin is usually stripped off. Just as an electric cord shorts out when its insulation is peeled away, the missing myelin disrupts the body’s ability to transmit sensory signals, resulting in paralysis.
Embryonic stem cells can turn into any type of tissue in the body. For Geron’s rat studies, the stem cells were developed into oligodendrocytes. These cells help nerve fibers replace myelin.
Geron spent $150 million over 13 years perfecting this treatment for spinal injuries. More than 250,000 people in the U.S. have paralyzing spinal injuries, with about 11,000 new cases reported each year. It’s too bad Christopher Reeve couldn’t live long enough to see it approved. That will be a great day, if GERN can complete the long and winding road through the FDA.
The company has assembled a 25,000-page filing just to ask permission to begin Phase I trials. They will file in the first half of this year, with no decision expected before the anti-embryonic stem cell Bush Administration leaves office. McCain, Clinton, and Obama all oppose Bush’s limits on funding for human embryonic stem cells.
Under the current regime, Geron had to use stem cell colonies that were not exposed to mouse skin cells, commonly used to provide nutrients to the stem cell culture, but capable of transmitting viruses. The FDA also made Geron show that injected rats stayed free of tumors or other side effects for up to a year. Because the rats were so severely injured, they had no control over their bodily functions, so lab technicians had to empty each rat’s bladder three times a day by hand for the whole year to keep the rats’ kidneys from failing. The next time you hear someone complaining about their job, ask them if they’d rather be a lab tech at Geron.
The stock jumped about 8% on this news. I expect it to take a bigger jump when Geron files for the Phase I human clinical trial, and a huge move up when they have the results. Buy GERN up to $9 for my $18 target.
ViroPharma (VPHM) reported earnings yesterday, with Vancocin sales up to $47.7 million from $38.5 million last year, and 25 cents a share. Analysts were looking for a bit more revenue, $50.4 million, but only 20 cents a share. The smaller loss was attributed to the fact that management is sourcing Vancocin from a different and cheaper contract manufacturer.
For the year, Vancocin sales hit $203.8 million, up 22.2% from $166.6 million in 2006. Management guided for 2008 Vancocin sales in the $210 million to $235 million range. The consensus was at $210 million, so this was an increase. At the high end of the range, Vancocin would show 15% growth for the year. Say, wasn’t this drug supposed to be wiped out by a generic by now?
There’s been little movement on that front, with the FDA still “thinking about it” in terms of whether generic companies will have to do human clinical trials. The FDA ruled that they did not, whereupon ViroPharma filed a couple of devastating briefs with the Agency asking them to reverse the ruling. In order to be effective against c.difficile, Vancocin has to be released in a certain segment of the intestine. It seems a little hard for a generic to demonstrate that in a lab test.
Meanwhile, the company is working on their own follow-on drug for c.difficile, still looking for takeover or in-licensing opportunities, and pursuing Camvia for CMV infections as an orphan drug in the U.S. and Europe. They are very well-positioned, although that is not reflected in the stock’s price.
It could be that before moving this stock up, Wall Street will wait for the FDA to formally say that they are withdrawing the generic Vancocin rules, or wait for ViroPharma to do an acquisition. In regard to the latter, the CEO has resigned to be with his family in France, and the CFO was promoted to CEO. Now, why would the right guy for the top slot right now be a financial guy? Answer: The company is going to do a big acquisition. You need to own it before that happens. Buy VPHM up to $12 for my $25 target.
New Energy Technology MegaShift
Oil prices broke through a new intraday high of $102 a barrel yesterday, due in part to another decline in the U.S. dollar and in part to a realization that any U.S. slowdown will be shallow and brief due to all of the government stimulus, both fiscal (thank you, Congress) and monetary (thank you, Bernanke Fed), being thrown at the economy. China and India are not slowing down, so energy consumption is headed up. I think that it is only a matter of time before all of our New Energy Technology stocks are recognized as living in a new world of permanently elevated petroleum prices.
Rentech (RTK) sent a President’s letter to shareholders outlining their strategy for getting coal-to-oil into mainstream production. Basically, they are paying the most attention to what to do with the carbon dioxide created by the process. In the Natchez plant, they will sell it for use in an industrial process. In other plants, it may have to be sequestered underground. A lot of venture capitalists are working on ways to use or fix carbon dioxide, and that work doesn’t cost RTK a penny.
Seward asked: “Oil is $100 a barrel and, while solar stocks have pulled back from their crazy highs, their performance indicates that alternative energy is of interest to the investing public. Would you do us the favor of discussing why Rentech has no traction in this market?”
Seward, I think that it is this carbon dioxide issue. Oil at these prices leaves lots of profit margin to invest in sequestering carbon dioxide, but a lot of investors would like to see a technology solution to get rid of it.
Carolyn wanted to know: “What event do you think is on the near-term horizon that will move that stock in a positive direction?”
There are at least two. One is the opening of their pilot plant in Colorado. The second is a contract from the Department of Defense for jet fuel. In addition to those, look for more contracts with coal companies as an additional driver for the stock.
Finally, Fred asked about Headwaters (HW) as a competitor to RTK. Headwaters has a wide range of businesses including architectural stone veneer and building materials, but the Hydrocarbon Technologies division focuses on upgrading heavy oil to a lighter, more valuable grade. They are applying some of that technology to coal liquefaction, providing coal to utilities in a form that, when burned, meets the EPA standards.
Their direct competition with Rentech is a project that they are doing with the Chinese government to convert coal to a synthetic diesel/jet fuel. I think there are issues with pollution and probably economics that make this process less competitive with RTK than appears on the surface. But I will watch Headwaters with interest, and may even recommend it some day, even though it is not nearly as pure a play on coal-to-synthetic fuel as Rentech. For now, buy RTK up to $4 for my $8 target.
WiMAX MegaShift
Airspan (AIRN) reported earnings last night, and the news was not good. Their legacy (non-WiMAX) products had very weak sales. For the December quarter, revenues fell 24% from last year, from $31.3 million down to $23.8 million. That was near the analyst consensus for $23.9 million. But the company lost 14 cents a share, compared with 10 cents last year and analyst expectations for an eight-cent loss. Stronger WiMAX sales growth might have made up for the rapid decline in legacy equipment sales, but that didn’t happen. The company guided for a seasonally weak March quarter, with sales of $20 million to $21 million, well below consensus expectations for $25.5 million.
The good news is that WiMAX accounted for 80% of their revenues in the December quarter, and it is growing 40% per year. The legacy business can’t drag them down much longer. In a December report, the market research firm Infonetics ranked Airspan #2 in equipment shipments across the spectrum, and #1 for certified, compliant mobile WiMAX equipment. Infonetics says that the industry is on an 80% annual growth rate path through 2010.
Due to the earnings report, AIRN was hit today, down 26 cents. I am reluctantly bringing my buy limit and target price down to reflect current market levels, but I still think owning the #2 company in WiMAX equipment is a great idea. Buy AIRN up to $3 for an $8 target.


